CYFRA 21-1 predicts the efficacy of nivolumab in patients with advanced lung adenocarcinoma
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چکیده
منابع مشابه
Postoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I pulmonary adenocarcinoma
BACKGROUND Patients with pathological stage I pulmonary adenocarcinoma have different postoperative prognosis. The aim of this study is to evaluate the prognostic significance of preoperative and postoperative serum levels of carcinoembryonic antigen (CEA) and CYFRA 21-1 in patients with pathological stage I pulmonary adenocarcinoma. MATERIAL AND METHODS We retrospectively reviewed the data o...
متن کاملPrognostic value of combination of Cyfra 21-1, CEA and NSE in patients with advanced non-small cell lung cancer.
OBJECTIVE To assess the value of Cyfra 21-1, carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) combined, all three together as prognostic factors in advanced stage non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS Serum samples from untreated NSCLC patients were prospectively collected. All assays were performed using commercial kits blind to clinical informati...
متن کاملCYFRA 21-1 serum analysis in patients with esophageal cancer.
This study was conducted to determine a potential use of CYFRA 21-1 in patients suffering from carcinoma of the esophagus. CYFRA 21-1 serum concentrations of 50 patients with histologically proven malignant lesion of the esophagus were compared with 50 healthy persons, 50 patients with benign esophageal disease, and 50 patients with benign lung disease. Additional analysis of serum carcinoembry...
متن کاملCYFRA 21-1 is an early predictor of chemotherapeutic effectiveness in advanced nonsmall cell lung cancer
Serum cytokeratin 19 fragment (CYFRA21-1) has been found to be a useful prognostic marker in lung cancer. Previous studies have revealed that change in CYFRA21-1 synchronously predicted therapeutic effectiveness in advanced nonsmall cell lung cancer (NSCLC) after the second cycle of chemotherapy. The objective of this study was to investigate the early predictive value of percentage change in s...
متن کاملDiagnostic Efficiency of HE4 and CYFRA 21-1 in Patients with Lung Cancer
Lung cancer is the leading cause of cancer related deaths. Despite the modern diagnostic and therapeutic advances, 5-year survival rate of all cases of lung cancer does not exceed 15%. Therefore, sensitive tumor biomarkers are needed for the early detection and differential diagnosis of lung cancer. The aim of the study was to evaluate the diagnostic efficiency of HE4 (Human epididymis protein ...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2018
ISSN: 1010-4283,1423-0380
DOI: 10.1177/1010428318760420